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| We produce bulk quantities of all recombinant proteins. |
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Recombinant Human VEGF
| Synonyms: | Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen |
| Description: | VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. |
| Source: | E.coli |
| Stability: | The lyophilized protein is stable for at least 2 years from date of receipt at -20C. Reconstituted VEGF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles. |
| Purity: | Greater than 99% by SDS-PAGE gel and HPLC analyses. |
| Biological Activity: | Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. |
AA Sequence: | APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR |
| 1 mg |
10 mg |
100 mg |
1 g |
| $2,000.00 |
$12,000.00 |
$60,000.00 |
$100,000.00 |
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