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| We produce bulk quantities of all recombinant proteins. |
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Recombinant Human G-CSF
| Synonyms: | Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, pluripoietin |
| Description: | G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues. |
| Source: | E.coli |
| Stability: | The lyophilized protein is stable for at least 2 years from date of receipt at -20C. Reconstituted G-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles. |
| Purity: | Greater than 99% by SDS-PAGE gel and HPLC analyses. |
| Biological Activity: | The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. |
AA Sequence: | TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP |
| 1 mg |
10 mg |
100 mg |
1 g |
| $2,000.00 |
$12,000.00 |
$60,000.00 |
$100,000.00 |
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